Description: Cytochrome P450 2E1: Its Role in Disease and Drug Metabolism Please note: this item is printed on demand and will take extra time before it can be dispatched to you (up to 20 working days). Author(s): Aparajita Dey Format: Hardback Publisher: Springer, Netherlands Imprint: Springer ISBN-13: 9789400758803, 978-9400758803 Synopsis The book deals with various clinical aspects of cytochrome P450 2E1 (CYP2E1) which is a potent source for oxidative stress. Oxidative stress is critical for pathogenesis of diseases and CYP2E1 is a major contributor for oxidative stress. Several clinical disorders are associated with changes in regulation of CYP2E1 and the consequent abnormalities which include alcoholic liver disease, alcoholic pancreatitis, carcinogenesis, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, obesity, hepatitis C virus infection, reproductive organ toxicity, hepatocellular and cholestatic liver cirrhosis, inhibition of bone repair, cross-tolerance in smokers and people treated with nicotine, disorders of central nervous system, changes in metabolism of protoxicants in the circulatory system and susceptibility to human papillomavirus infection. Hence, CYP2E1 emerges as a new and potent player in aggravating injury and furthering disease complications.
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Book Title: Cytochrome P450 2E1: Its Role in Disease and Drug Metabolism
Number of Pages: 256 Pages
Language: English
Publication Name: Cytochrome P450 2e1: Its Role in Disease and Drug Metabolism
Publisher: Springer
Publication Year: 2013
Subject: Medicine, Chemistry
Item Height: 235 mm
Item Weight: 5817 g
Type: Textbook
Author: Aparajita Dey
Series: Subcellular Biochemistry
Item Width: 155 mm
Format: Hardcover
